Anti-Aging Benefits of Glutathione

L-glutathione is the most abundant amino acid found in skeletal muscle.  It is also a potent antioxidant, enzyme cofactor, and detoxifier.   As such, it has an important role in The Kitchen Sink™ formula.

Liver Disease

In various liver diseases (fatty liver, acute and chronic hepatitis, cirrhosis, etc.), a four-to-eight-fold decrease in GSH was observed.  The investigators postulated that low GSH contributed to liver injury.  Pre-treatment with GSH offered significant protection in these clinical trials.

Lung Disease

GSH deficiencies have been documented in a number of pulmonary diseases, including acute respiratory distress syndrome, asthma, chronic obstructive pulmonary disease, etc.  When GSH levels were brought up to normal, patients improved significantly.

Immunity

The proliferation, growth, and differentiation of immune cells are dependent on GSH.  Both the T and the B lymphocytes require adequate levels of GSH for differentiation.  Patients with low GSH levels were found to have significantly lower CD4count.  Low GSH status is of particular importance in patients with HIV and/or autoimmune diseases e.g. systematic lupus erythematosis and rheumatoid arthritis.

Cerebral Dysfunction

The brain is highly oxygenated and has highly saturated lipid content and is therefore particularly vulnerable to peroxidation.  Parkinson’s disease, schizophrenia and Tardive dyskinesia have been linked to free-radical overload with corresponding reduced levels of cellular GSH.

Atherosclerosis

Atherosclerosis appears to be linked to oxidative damage to the vessel wall.  Increased lipid peroxides, decreased GSH peroxidase and prostacyclin (PGI2) have been documented in human and animal atherosclerotic arteries.

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